Completed Project

Interventions to increase immunization coverage among children 12-23 months of age in India through participatory learning and community mobilization: cluster randomized trial

Agency : CHUM (Centre Hospitalier De L’Universite De Montreal)

Team Alok Mathur

The study aimed to evaluate the impact, cost-effectiveness, scalability and sustainability of participatory, community-based knowledge transfer and education (KTE) interventions to improve coverage of basic vaccines among children less than 24 months from undeserved communities in India. It was hypothesized that participatory, community-based KTE interventions could increase vaccination coverage in hard-to-reach populations. Trial design: Cluster-randomized, stratified, superiority trial with two parallel groups and a 1:1 allocation ratio to investigate the effectiveness of participatory, community-based KTE interventions versus usual care on the primary endpoint of receipt of third dose of pentavalent (Hemophilus Influenza Type B, diphtheria-tetanus-pertussis (DTP), and Hepatitis B) (PENTA 3) vaccine among children 12-23 months.  The aim of this pilot study was to assess study processes and feasibility and aid in refining methods for the larger study.